COVID-19: Pfizer’s Paxlovid Approved by FDA; CDC Updates COVID-19 Community Levels

**Emergency Use Authorization for Paxlovid**

The U.S. Food and Drug Administration (FDA) has granted emergency use authorization (EUA) for Pfizer’s COVID-19 oral antiviral treatment, Paxlovid. The pill combines two antiviral medications, nirmatrelvir and ritonavir, to target the SARS-CoV-2 virus and prevent it from replicating.

Paxlovid is intended for the treatment of mild to moderate COVID-19 in adults and children (12 years of age and older, weighing at least 40 kilograms) who are at high risk for progression to severe COVID-19, including hospitalization or death.

The EUA is based on data from a clinical trial that showed Paxlovid reduced the risk of hospitalization or death by 89% in high-risk patients who received the treatment within five days of symptom onset. The most common side effects reported in the trial were taste disturbance, diarrhea, nausea, and vomiting.

Paxlovid is taken as three tablets (two tablets of nirmatrelvir and one tablet of ritonavir) twice a day for five days. The course of treatment should be started as soon as possible after a positive COVID-19 test and within five days of symptom onset.

**Updated CDC COVID-19 Community Levels**

The Centers for Disease Control and Prevention (CDC) has updated its COVID-19 Community Levels to reflect the current state of the pandemic in the United States. The levels are based on three metrics: new COVID-19 cases per 100,000 population, the percentage of COVID-19 hospital beds occupied, and the percentage of COVID-19 deaths per 100,000 population.

Counties are assigned a community level of low, medium, or high based on the combination of these metrics. The CDC recommends different public health measures for each level, such as mask-wearing, social distancing, and testing.

According to the latest update, most counties in the United States are now at a low or medium community level. However, there are still some counties that are at a high community level, particularly in the Northeast and Midwest. The CDC continues to urge people to take precautions to protect themselves and others from COVID-19, regardless of the community level in their area.

**Conclusion**

The FDA’s authorization of Paxlovid and the CDC’s updated COVID-19 Community Levels are important steps in the ongoing fight against the pandemic. Paxlovid provides a new treatment option for people at high risk for severe COVID-19, and the updated community levels help guide public health measures and personal decisions about how to protect from the virus..

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